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Since your connection involving PKC�� along with Smac is associated with tactical in your studies, that suggests a mechanism that can no less than in part describe a great anti-apoptotic effect of PKC��. These facts offer cell-specific conditions might determine whether PKC�� offers mostly a great anti- or even pro-apoptotic position. To conclude, we display a currently uncharacterized conversatio
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we have recently made use of the coumarin scaffold and introduced an azide function at position 7, in order to study alkylation specificity of the resulting compound termed N3BC [37]. In our hands, N3BC displayed selectivity for uridine over the other major ribonucleotides, but not for pseudouridine. N3BC contains an electron withdrawing azide substituent where the presumed -selective BMB contains
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